Liver Function Tests

Liver Function Tests (LFT) – A Comprehensive Liver Health Assessment

Liver Function Tests (LFTs) are a group of blood tests that provide valuable information about the state and functionality of the liver. These tests are crucial for diagnosing and monitoring liver diseases, liver damage, or abnormalities that may affect this vital organ’s performance.

The LFT panel includes several important parameters:

• Bilirubin (Total, Direct, and Indirect): Measures the levels of bilirubin, a waste product formed from the breakdown of red blood cells. Elevated levels can indicate liver dysfunction, bile duct obstruction, or hemolysis.

• SGOT (AST) and SGPT (ALT): These enzymes are released into the bloodstream when liver cells are damaged. High levels are commonly associated with liver inflammation, hepatitis, alcohol-related liver injury, or drug toxicity.

• Alkaline Phosphatase (ALP) and GGT (Gamma-Glutamyl Transferase): These enzymes help identify bile duct disorders. Elevated ALP or GGT may suggest cholestasis, gallstones, or bile duct obstruction.

• Total Protein, Albumin, and Globulin: These assess the liver’s ability to synthesize essential proteins. Low albumin levels may indicate chronic liver disease, malnutrition, or kidney problems.

By analyzing these markers, physicians can detect a wide range of liver-related issues—from mild inflammation to severe cirrhosis. LFTs also play a key role in monitoring liver disease progression, evaluating the effects of medications, and guiding treatment strategies. For patients with symptoms such as jaundice, fatigue, dark urine, or abdominal pain, LFTs are essential in reaching an accurate diagnosis.

Regular liver testing is especially important for individuals with a history of alcohol use, hepatitis, obesity, or chronic medication use.